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The application of plasma generator in the treatment of adhesion and proliferation of PEGDA-based gel surface

The application of plasma generator in the treatment of adhesion and proliferation of PEGDA-based gel surface: The adhesion of target cells to biological materials is a prerequisite for the construction of tissue-engineered organs. Materials with good cell compatibility provide a good extracellular growth environment for cells, and maintain the normal phenotype and physiological functions of cells, and realize the restoration of tissue or organ structure and function. Polyethylene glycol (PEG) is a non-degradable polymer biomaterial approved by the US FDA. It has hydrophilicity, biocompatibility, and inhibits protein adsorption and cell adhesion. Low-molecular-weight PEG can be swallowed by phagocytes or excreted through the kidney membrane. Although the surface of the PEG-loaded material has good biocompatibility, it is difficult for cells to adhere to the surface of the material due to its resistance to proteins and cells. And growth. Therefore, the PEG substrate is activated and modified by introducing active groups, so that it can be used to construct desired biological functional materials. The chemical functional groups on the surface of biological materials (such as hydroxyl, amine, carboxyl, carbonyl, amide, etc.) have an important impact on cell compatibility and affect the hydrophilicity and hydrophobicity of the material. The hydroxy Z methacrylate monomer with active hydroxyl groups was introduced into the polyethylene glycol diacrylate substrate. The research results show that the hydroxyl groups are beneficial to cell adhesion and spreading, thereby improving the cells of PEGDA-based gel materials. Affinity; On the other hand, the surface energy of the material has an important effect on cell compatibility. It is generally believed that higher surface energy is beneficial to cell adhesion, spreading and proliferation. The use of plasma generator glow discharge surface modification technology can improve some Polar oxygen-containing and nitrogen-containing groups (such as amino and amide groups) are introduced into the surface of chemically inert materials to improve their biocompatibility. The surface roughness of the material after plasma treatment by the plasma generator is increased, and the increased surface can enhance the cell affinity of the material. After the material is plasma treated, due to the action of free radicals, electrons and ions in the plasma, the chemical bonds on the surface of the material are broken to form new chemical bonds, and the distribution of electrons near the elements also changes. The interaction between cells and matrix materials is the main field of tissue engineering research. Among them, the adhesion of cells and materials is the basis. Cells must properly adhere to the materials in order to migrate, proliferate and differentiate. The surface roughness and hydrophobicity of the materials are related to The surface energy of materials is closely related, which affects cell adhesion and proliferation. After the plasma surface treatment by the plasma generator, the surface of the membrane material is rougher than that before treatment, with uneven, undulating height, which can increase the surface area of ​​the contact between the cells and the material, and at the same time facilitate the extension of the filopodia at the cell protrusions. The filopodia are beneficial to the adhesion and spreading of cells on the surface of the material. After the material is treated with plasma, the hydrophilicity and surface energy of the material are greatly enhanced, which promotes the wetting effect of the cells on the surface of the material, and the rough surface improves the adhesion of the cells. The material modified by the plasma generator ion surface showed better cell proliferation than the unmodified membrane surface, and the cell adhesion rate was increased. The proliferation of the material after plasma treatment was generally more active than that before the treatment, and the plasma treatment condensed The film material is more conducive to the proliferation and growth of BMS on the material. Plasma-treated materials have stronger cell adaptability than untreated materials, have a higher adhesion rate, vigorous proliferation in vitro, stable growth characteristics, and form a network structure.

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The pretreatment of the plasma cleaner can significantly improve the bonding strength of the stainless steel surface coating

The pretreatment of the plasma cleaner can significantly improve the bonding strength of the stainless steel surface coating: Due to its good mechanical properties, ease of processing and reliability, stainless steel is widely used in human implant materials, but due to the shortcomings of the metal itself such as thrombosis and poor corrosion resistance, the biocompatibility of stainless steel materials Not very ideal. A large number of clinical application results show that after the stainless steel artificial heart valve vascular stent is implanted in the human body, various degrees of thrombus and other adverse symptoms caused by thrombus appear on the surface of the material. Therefore, the research on how to improve the blood compatibility and histocompatibility on the surface of stainless steel materials is quite active. Among them, the method of introducing inorganic polymer materials or drugs with therapeutic effects on the surface of the materials has attracted widespread attention. In the study of various surface modification methods, the bond firmness between the coating and the substrate is an important parameter. There are many factors that affect the bonding strength between the coating and the metal substrate, such as the nature of the coating material, the chemical state and roughness of the substrate surface, the coating process, and so on. At present, most of the chemical and physical methods are used to change the chemical state or roughness of the substrate surface to improve the bonding strength between the coating and the substrate. The plasma technology process is one of the more commonly used physical treatment methods. Compared with traditional chemical methods, plasma modification belongs to a gas-solid coherent reaction system, which has the advantages of greatly improving the bonding strength between the coating and the substrate, and does not introduce other substances and does not pollute the environment. Analysis of samples after plasma treatment with a plasma cleaner revealed that the bonding strength of the surface coating of the material has been significantly improved, and the bonding strength of the surface has been enhanced. It can be seen that plasma treatment of stainless steel is an effective measure to improve the bonding strength of its surface coating. There is a layer of metal oxide and metal hydroxide on the surface of stainless steel that has been in the atmosphere for a long time. Between the metal oxide and metal hydroxide, a layer of hydrocarbon compounds is adsorbed on it. Despite a series of ultrasonic cleaning, a small amount of organic pollutants and cleaning solvents may still remain on the surface of the substrate. The surface of the sample without plasma treatment is covered with hydrocarbon compounds, and the plasma can completely remove the hydrocarbon compounds adsorbed on the surface of the stainless steel. After the plasma treatment of the plasma cleaner, the carbon hydrocarbon compounds adsorbed on the surface of the stainless steel are basically removed. The improvement of the surface cleanliness of the material is beneficial to improve the van der Waals force between the coating and the substrate. Plasma pretreatment can significantly improve the bonding strength of the stainless steel surface coating. After plasma treatment, the increase in the bonding strength of the film base is mainly related to the cleaning and etching of the surface of the base body. The increase in the bonding strength of the film substrate after plasma cleaning machine treatment is mainly due to its cleaning and activation of the substrate surface.

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Low-temperature plasma surface processor is used for surface cleaning and modification applications of medical catheters

Low-temperature plasma surface processor is used for surface cleaning and modification applications of medical catheters: Medical catheter is a kind of medical equipment. Its hierarchical management is relatively strict, and safety and reliability requirements are high. In the surface treatment of low-temperature plasma surface processor, it is often used in the surface modification technology of medical catheter. In the medical field, there are many devices that can directly or indirectly contact the human body. The domestic management of medical devices is also very strict. The higher the level of the device, the higher the process requirements. The use of low-temperature plasma surface processors for surface modification of materials has become indispensable. One ring. Plasma surface treatment in the field of medical equipment, including surface cleaning, etching, coating, polymerization, disinfection, etc., can improve the surface modification properties of materials and improve their hydrophilic, hydrophobic, air-permeable, and blood-soluble functions. The application of low-temperature plasma surface processor on medical catheters is mainly used for the treatment of anti-jun catheters before coating to improve the hydrophilicity and wettability of materials. Chengfeng Zhizhuang low-temperature plasma surface processor has rich experience in surface modification of medical catheters and has the following characteristics: 1. Plasma surface treatment equipment for medical catheters, used in conjunction with a customized grafting instrument to improve the surface hydrophilicity of rubber materials; 2. The structure design of multilayer vertical electrodes; 3. The product adopts a specially designed rack structure, which is convenient to use; 4. It can meet the surface treatment of the inner wall of the urinary catheter; 5. It can be used to process other medical devices. The plasma surface treatment equipment was developed by Chengfeng Zhizhi Manufacturing Company to improve the hydrophilicity, biocompatibility and bonding ability of materials. If you want to know more about the low-temperature plasma surface processor, or have any questions about the use of the equipment, please click the online customer service of Chengfeng Zhizao, and Chengfeng Zhizao is waiting for your call!

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The etching of wafer circuit board plasma cleaning machine is applied in the circuit board industry

The etching of wafer circuit board plasma cleaning machine is applied in the circuit board industry: Most of the gases used in plasma etching are fluorine-containing gases, of which carbon tetrafluoride is the main one. Plasma cleaner etching is widely used in wafer manufacturing and circuit board manufacturing. Application of wafer manufacturing industry: In the wafer manufacturing industry, photoetchers use tetrafluorocarbon gas to etch silicon wafers, and plasma cleaners use tetrafluorocarbon gas to etch silicon nitride and remove photoresist. Plasma etching uses pure carbon tetrafluoride gas or the combination of carbon tetrafluoride and oxygen to perform micron-level etching on silicon nitride during the wafer manufacturing process. Under the combination of hydrogen and oxygen, the micron is removed. Grade photoresist. Application of circuit board plasma cleaning manufacturing industry: The etching of plasma cleaning machine has been applied very early in the circuit board industry. Whether it is a rigid circuit board or a flexible circuit board, the phenomenon of glue removal in the hole will occur during the production process. The traditional processing method is to use chemical agents to clean, but with With the development of the circuit board industry, the boards are made smaller and smaller, and the holes become smaller. It is more and more difficult to remove glue in the chemical cleaning holes. Also, the smaller the hole, the erosion amount is difficult to control, and chemical residues will be generated. Affect the subsequent processing. However, the etching of the plasma cleaner is dry, there is no chemical residue, and the plasma has a very strong diffusion ability. The generated etch gas-phase plasma can be effectively etched in the micron-level holes, and the amount of biting is It can also be controlled by adjusting the process parameters. Chengfeng Zhizhi has focused on the research and development of plasma cleaning machines for 20 years. If you want to know more product details or have questions about the use of the equipment, please click on Chengfeng Zhizhi online customer service, waiting for your call!

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Chengfeng Zhizhi plasma cleaning machine manufacturer explains the role of silicon wafers in the manufacture of silicon cells

Chengfeng Zhizhi plasma cleaning machine manufacturer explains the role of silicon wafers in the manufacture of silicon cells: Common lithium batteries should be considered lithium-ion batteries. Portable electronic products such as laptop computers, video cameras, and mobile communications are widely used in our daily lives. Now it is also developing silicon batteries, which are expected to be applied to mobile phone batteries. The following is a detailed explanation of the plasma cleaning machine manufacturer made by Chengfeng Zhizhi. Nowadays, the smartphones in our hands are basically lithium batteries, and battery technology is also one of the difficulties in today's smart technology demand breakthrough. According to foreign media reports, a startup company called XNRGI wants to break this situation and plans to release it next year. It produces a higher energy density, lower manufacturing cost, and safer use than traditional lithium-ion batteries. In addition, the company uses a method similar to that used by semiconductor companies to manufacture processors, using wafers to make silicon cells. At present, the plasma cleaning machine manufactured by Chengfeng Zhizhi is mainly used for the cleaning of silicon wafers and the removal of photoresist. Therefore, people are also very interested in this method of using silicon wafers to manufacture batteries. At present, XNRGI has been researching and developing silicon batteries for 15 years. Its energy density is 4 times that of lithium batteries, and its cost is only half of that of lithium batteries, and its "porous" silicon batteries can be used in many scenarios, such as Many smart terminals such as smart phones. The manufacturing principle of this battery is to etch very fine 20×20 micron honeycomb images on these wafers, and then coat them with lithium and other metals to form the anode and cathode of the so-called "microbattery", that is, every 12 An inch silicon wafer contains 36 million such vertical micro-cells (with an energy density of more than 400Wh/kg), which constitute a macro battery. Because of this unorthodox structure, charging is faster. XNRGI's batteries are recyclable, unlike traditional lithium-ion batteries that are as easily thermally out of control. Their energy density exceeds 400Wh/kg, which makes them cheaper to manufacture, so they are very suitable for storing electric vehicles and grids. If you want to learn more about the plasma cleaner or have questions about the use of the equipment, please click on the online customer service of Chengfeng Zhizao, and Chengfeng Zhizao is waiting for your call!

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Introduction of dry screw vacuum pump and its characteristics of vacuum plasma power supply equipment

Introduction of dry screw vacuum pump and its characteristics of vacuum plasma power supply equipment: Dry vacuum pump is an abbreviation of dry mechanical vacuum pump. Dry vacuum pump is a common type of vacuum pump on vacuum plasma power equipment. According to the knowledge of practitioners, dry vacuum pump is more reliable and durable. Let Cheng Fengzhi introduce the dry vacuum pump and its characteristics. What is a dry vacuum pump? Dry vacuum pump is a vacuum pump that does not use liquid as a working medium, such as oil, water or other polymers. This can make dry vacuum pumps better in cleaning and prevent oil pollution. Therefore, dry vacuum pumps are mainly used in vacuum plasma power equipment, which requires high cleanliness, such as semiconductors, biomedicine, aerospace and other fields. Dry screw vacuum pump is a commonly used type of vacuum plasma power equipment. Dry screw vacuum pump: The dry screw vacuum pump is a vacuum pump that uses a pair of screws to rotate synchronously in the vacuum pump housing at high speed and reverse to generate force to achieve suction and discharge functions. As the dry screw vacuum pumps are working, there is no friction between each other, smooth operation and low noise, so there is no need for lubricating oil in the working cavity. The advantages of dry screw vacuum pumps; The dry screw vacuum pump is a dry vacuum pump with excellent performance. Compared with other vacuum pumps, it has many advantages: First, the vacuum of the dry screw vacuum pump is very high, and the vacuum can reach 1~2 Pa; Second, the dry screw vacuum pump has stable performance, is not prone to failure, has low noise, and is easy to maintain; In addition, the working cavity of the dry screw vacuum pump and the surface of the screw rotor have anti-corrosion coatings, which are more suitable for harsh working conditions. The working principle and advantages of the screw vacuum pump commonly used in the dry vacuum pump on the above-mentioned vacuum plasma power supply equipment. After reading the above content, have you found the fundamental reason for the reliability and durability of the dry vacuum pump. If you are interested in plasma cleaners or want to know more details, please click Chengfeng Zhizao online customer service consultation, Chengfeng Zhizao is waiting for your call!

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