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Research status of biomedical metal material modification application by low temperature plasma technology

Research status of biomedical metal material modification application by low temperature plasma technology: Due to the development of basic industries and high-tech products, people's demand for high-quality, high-efficiency surface modification and coating technology is developing in depth. Breakthrough progress has been made in surface modification and coating process simulation and performance prediction. As an important part of the development of new metal biomaterials, low temperature plasma technology surface modification and coating technology has penetrated into traditional industries and high-tech industrial sectors, and further promotes the development of surface functionalized coating technology according to application needs. In the low temperature plasma surface modification technology, it is an important research direction to design the material surface according to the application requirements, tailor the material surface performance parameters to meet the special requirements, and further realize the prediction of the structure and properties of the surface covering layer. Different types of Plasma Chemical Vapor Deposition (PCVD) is a challenging research topic that is being carried out by research institutes and universities. Computer simulation studies on Plasma Chemical Vapor Deposition (PCVD) and other surface modification methods have been carried out abroad. , The PCVD process was simulated, and the macro and micro multi-level models were used to simulate and predict the various properties of the plasma process and coating and the bonding force of the substrate; Simulation allows for better control and optimization of the process. For half a century of the 20th century, the ideas and methods of physics dominated the discovery and preparation of new materials. Since the 1950s, the ideas and methods of molecular biology have been rapidly recognized as the guiding principles for the growth, discovery and crystallization of new materials. & Since most biological reactions occur at the interface and surface of materials, biologists introduce surface science into biology, which plays a decisive role in the development of biomedical materials, biomedical materials and devices have the ability to save human lives, huge The commercial value of it has strongly stimulated a lot of research. Since low-temperature plasma technology has unique advantages and potentials in the growth of biomedical materials and the fabrication of biomedical devices, if the two are organically combined, it is possible to realize the revolutionary development of biomedical technology in the 21st century. In the future, with the development of plasma surface modification technology at home and abroad, combined with the needs and status of biomedical engineering, we will focus on the development of a number of advanced and applicable key technologies for surface functionalization of metal materials, including low-temperature plasma vapor deposition technology and equipment. , Numerical simulation of surface coating process and quality, and research and development of optimal control. What we mean by biomedical materials refers to materials that are compatible with living organisms involved in biomedical research and medical practice, including materials for the manufacture of artificial organs, biosensing materials, external surface materials for in vivo implantation devices, and certain materials. The materials used in some medical devices, the surface reaction of these materials is mainly controlled by the surface chemistry and molecular structure of the materials, which requires biomedical materials not only to have certain physical properties such as strength and elasticity, but also to have a biocompatible surface. nature. It is quite difficult to design a new material with both the required physical properties and the required surface properties. Since the response of organisms to the material surface mainly depends on the chemical properties and molecular structure of the material surface, it is possible to choose existing materials. Surface modification of the material with the required body properties to make it have the required biocompatibility, so as to achieve the above purpose, for example, some macromolecular polymers have similar mechanical properties to human organs, but are not biocompatible Therefore, surface modification is required to fix specific functional groups on the surface to achieve the purpose of being compatible with living organisms. In conclusion, low-temperature plasma technology is being applied by many scientists in the research of surface modification and surface film synthesis of metal biomaterials due to its unique advantages, but most of these studies are still in the development or experimental stage. Low-temperature plasma surface modification technology, with the deepening of plasma theoretical research and the resolution of process problems, will definitely improve the biologi

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Research on the reduction of bacterial adhesion and modification of aluminum sheets after plasma treatment

Research on the reduction of bacterial adhesion and modification of aluminum sheets after plasma treatment: During the production, packaging and transportation of medicines and food, bacteria in the environment can easily adhere to their surfaces to form a biofilm, causing contamination of medicines and reducing the shelf life of food production, thus affecting people's health. A step in biofilm formation is the adsorption of macromolecules such as bacteria and proteins. If the surface material can prevent bacteria from sticking, it can prevent the formation of biofilms. Polyethylene glycol (PEG) organic compounds are potential preservatives that can effectively prevent bacteria and proteins from adhering. Aluminum is a common packaging material widely used in the food and pharmaceutical industries. If polyethylene glycol is used to deposit a reinforcing film on the surface of the aluminum sheet, it can prevent bacteria from adhering. Surface modification methods include chemical and physical methods. The chemical method is a wet method, and its technological operation is relatively complicated, and chemical reagents that pollute the human body and the environment are required. Low-temperature plasma technology opens up a new avenue for surface modification of metal biomaterials. It is a dry process with the advantages of easy operation and control, no pollution to the environment, and has received more and more attention in the fields of food and biomedicine. The PEG-like structure was grafted on the surface of the aluminum sheet by low-temperature plasma to form a thin film, and a large number of -CH-CH-O bonds were mainly accumulated on the surface; Greatly reduces bacterial adhesion. Plasma-induced reactive species (such as free radicals, etc.) provide a mechanism for the recombination of surface di(ethylene glycol) methyl ether molecular fragments for reaction. The free radicals fall into the newly generated macromolecular network and can initiate a vigorous electronically excited in situ oxidation reaction. The ATR-FTIR analysis of the aluminum sheet macromolecular layer structure after plasma treatment shows that there is a strong absorption peak at 1583.07 cm, which is the characteristic absorption peak of the CO bond in the PEG structure, indicating that the deposited surface layer is PEG-like. structure. The absorption peak at 1780.21cm indicates that there is a C-O bond, which shows that a partial cross-linking reaction occurs while forming a PEG-like structure. Compared with before modification, the bacterial adhesion of aluminum sheet after plasma treatment is greatly reduced after plasma treatment. This is because PEG structure is produced by cross-linking on the surface, and the PEG molecular chain has high flexibility. It can reduce the configurational freedom of macromolecular chains such as bacteria, and thus have the ability to resist bacterial adhesion. The surface morphology of the bacteria biofilm adsorbed on the aluminum sheet before modification and the sample analysis of the surface adsorption on the aluminum sheet after modification can be known that the surface of the modified aluminum sheet can effectively resist bacterial adsorption after plasma modification. The elemental composition and chemical bond state on the surface of the aluminum sheet changed significantly after plasma treatment, and CO, OCO and O-CO-O bonds were formed on the surface layer. This indicates that plasma-induced reactive species (such as free radicals, etc.) provide a mechanism for the recombination of surface bis(ethylene glycol) methyl ether molecular fragments, which is different from non-oxidative reactions in which the formed free radicals fall into newly generated macromolecules. In the network, a vigorous electronically excited in-situ oxidation reaction can be initiated. The PEG-like structure deposited on the surface of the aluminum sheet can greatly reduce bacterial adhesion. Compared with before modification, bacterial adhesion is reduced by more than 80%, which has important application prospects in the food industry and medical transplantation.

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You are familiar with the use of plasma in these fields and the future of low temperature plasma

You are familiar with the use of plasma in these fields and the future of low temperature plasma: With the development of technology, it is not just something we are usually familiar with. Plasma has a wide range of applications in science, economy, medicine and other fields, and plasma is one of them. Plasma, like cryogenics, is a term for a state of matter. There are three types of substances: solid, liquid, and gas. Except for solid, liquid, and gas, other substances are now called plasma. If the gas is heated to an ultra-high pressure, it produces a mixture of various ions, electrons, and free radicals, known as plasma. Its variety and composition are complex, including various polymer plastics, metals, semiconductors, rubber, silicone, leather, circuit boards, etc. Such materials have poor surface properties and are prone to problems such as coating, bonding, and printing. In order to facilitate painting and printing, manual grinding was generally used in the past, which was not efficient and seriously affected the beauty of the interior. It will also open the glue. The cost of using hot melt glue and other high-grade glues is high, and it will also affect the reputation of the entire car brand. However, the application of plasma has been widely known. The plasma cleaning machine for automobile interiors produced by plasma treatment technology can improve the resistance to printing, abrasion, bonding and other issues. What are the car interiors? , steering wheel, instrument panel, seat system, air bag, seat belt, carpet, GPS, DVD, sensors, antenna, etc. The product has the characteristics of strong adaptability, energy saving, low energy consumption, strong equipment matching ability, safety and reliability. Therefore, it has been widely used in various aspects and is well-known by people from all walks of life. In industrial production, plasmas are used to create new materials with exceptionally superior properties. Materials such as semiconductors can also be used to sharpen knives, molds, etc., and sometimes to refine metals. Indeed, in industry, plasma technology is also used to make various tools. In the field of chemistry, plasmas are used to develop new chemicals and chemical processes. Sometimes, plasma technology is also used to treat hazardous waste. In the medical field, plasma is used for a variety of safe and adaptable procedures. It can not only ensure the effective operation of the operation, but also reduce the worry of the patient and reduce the risk of the scalpel. In addition, plasma equipment can also be used to make low-temperature plasma equipment, such as low-temperature plasma organic waste gas purifiers. Low temperature plasma technology can be used in various fields, not only in chemical and industrial fields, but also in a wide range of fields. The emergence of low-temperature plasma has solved many problems faced by people and made great contributions to people's lives.

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The 10 major functions of plasma surface treatment equipment in the manufacture of auto parts

The 10 major functions of plasma surface treatment equipment in the manufacture of auto parts: In recent years, plastics have been used more and more in the automobile manufacturing industry. At present, the amount of plastics used by well-known foreign automobile manufacturers generally accounts for 10-15% of automobile materials, and some even exceed 20%. Whether it is automotive exterior parts, interior parts, car headlights, weather strips, or functional and structural parts, the shadow of plastic products can be seen everywhere. The continuous improvement of the hardness, strength and tensile properties of industrial plastics has promoted the development of the automotive plasticization industry. Using plastic instead of steel can greatly reduce the weight of the car itself, thereby reducing fuel usage and lowering emission standards. Before painting, the plasma surface treatment machine equipment can perform surface activation cleaning on the protective rod of PP/EPDM composite before painting. As an independent component, the shock absorber not only beautifies the appearance of the car, but also has an important impact on the safety protection and aerodynamic performance of the car. In order to reduce fuel consumption and fuel costs and achieve low emission standards, lightweight, dense and corrosion-resistant plastic materials have gradually become the main material for automobile bumpers, and the amount of plastic materials has increased year by year. To ensure the internal and external quality of the product, the surface treatment of plastic needs to be better than that of steel. Through a variety of data comparisons, the plasma surface treatment machine equipment has a good treatment effect, can be processed online, has low cost, energy saving and environmental protection, and is currently an ideal treatment process in this field. The car bumper is treated with plasma surface treatment equipment. After spraying, it can be as glossy as the car body, so that the appearance of the car is more integral, and it can also cover the defects such as patterns and scratches on the plastic surface and improve the surface hardness. , in the UV exposure, durability, weather resistance, chemical resistance, dust resistance and other aspects can achieve good results. Moreover, PP plastic and EPDM plastic are cheap, easy to process and form, and have good elasticity, so they stand out among many automobile bumper manufacturers and are very popular. At present, the plasma surface treatment machine equipment has been widely used in various rubber sealing rings (door frame sealing ring, door head, window guide groove, window side sealing ring, front and rear windshield and front and rear cover plate sealing ring, engine sealing ring), Headlights, automotive interiors (air-conditioning vents, dashboards, airbags, GPS, DVD, meters, sensors, antennas), brake pads, oil seals, bumpers, etc. Be the first choice for improving part bonding. However, if PP/EPDM has not undergone plasma surface treatment, the surface energy of the plastic is low, the wettability is poor, the crystallinity is high, the molecular chain is non-polar, and the boundary layer is weak. These factors will cause poor spraying effect. Optional Chengfeng Zhizhi plasma surface treatment machine equipment can effectively remove the chemical substances that migrate to the surface introduced during processing into plastic products, as well as the negative effects of pigments and fillers on the coating, and pollutants such as dirt generated during transportation , so that the C-C or C-H bond on the surface of PP/EPDM material is oxidized to generate active matrix, such as C-O, C=O and COO, etc., which greatly improves the surface activity of PP/EPDM material. Improve the reliability and stability of automobile bumper spraying, so that the yield is greatly improved.

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You are familiar with the use of plasma in these fields and the future of low temperature plasma

You are familiar with the use of plasma in these fields and the future of low temperature plasma: With the advancement of technology, it is not just something we are usually familiar with. Plasma has a wide range of applications in science, economy, medicine and other fields, and plasma is one of them. Plasma, like cryogenics, is a term for a state of matter. There are three types of substances: solid, liquid, and gas. Except for solid, liquid, and gas, other substances are now called plasma. If the gas is heated to an ultra-high pressure, it produces a mixture of various ions, electrons, and free radicals, known as plasma. Its variety and composition are complex, including various polymer plastics, metals, semiconductors, rubber, silicone, leather, circuit boards, etc. Such materials have poor surface properties and are prone to problems such as coating, bonding, and printing. In order to facilitate painting and printing, manual grinding was generally used in the past, which was not efficient and seriously affected the beauty of the interior. It will also open the glue. The cost of using hot melt glue and other high-grade glues is high, and it will also affect the reputation of the entire car brand. However, the application of plasma has been widely known. The plasma cleaning machine for automobile interiors produced by plasma treatment technology can improve the resistance to printing, abrasion, bonding and other issues. What are the car interiors? , steering wheel, instrument panel, seat system, air bag, seat belt, carpet, GPS, DVD, sensors, antenna, etc. The product has the characteristics of strong adaptability, energy saving, low energy consumption, strong equipment matching ability, safety and reliability. Therefore, it has been widely used in various aspects and is well-known by people from all walks of life. In industrial production, plasma is usedTo manufacture new materials with special and excellent properties. Materials such as semiconductors can also be used to sharpen knives, molds, etc., and sometimes to refine metals. Indeed, in industry, plasma technology is also used to make various tools. In the field of chemistry, plasmas are used to develop new chemicals and chemical processes. Sometimes, plasma technology is also used to treat hazardous waste. In the medical field, plasma is used for a variety of safe and adaptable procedures. It can not only ensure the effective operation of the operation, but also reduce the worry of the patient and reduce the risk of the scalpel. In addition, plasma equipment can also be used to make low-temperature plasma equipment, such as low-temperature plasma organic waste gas purifiers. Low temperature plasma technology can be used in various fields, not only in chemical and industrial fields, but also in a wide range of fields. The emergence of low-temperature plasma has solved many problems faced by people and made great contributions to people's lives.

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Today, Chengfeng Zhizao will analyze the precautions for the power supply of low-temperature plasma cleaning equipment

         The following will tell you a few things that basically all types of low-temperature plasma cleaning equipment should pay attention to when using it. Now with the development of science and technology, there are more and more types of low-temperature plasma cleaning equipment. It is only necessary to understand the instructions for use. Some low-temperature plasma equipment also require operators to receive on-the-job training. With the development of science and technology, many low-temperature plasma equipment has begun to have a self-cleaning function, and the daily maintenance of the equipment has become more concise. In the experiment, when we want to clean, activate, corrode, deposit or polymerize the surfaces of various materials, low-temperature plasma processing equipment is a necessity, and as a high-precision equipment often used in laboratories, the price is naturally high. If Improper operation when using low-temperature plasma equipment is likely to cause damage to the equipment or affect the operation results, so today Chengfeng Zhizao will tell you about the precautions for the use of low-temperature plasma cleaning equipment. First, the low-temperature plasma cleaning equipment requires a power supply with a frequency of 220V AC and a frequency of 50HZ during operation. The connection and inspection of the power supply should be done before turning on the equipment. After the equipment is running, it should emit a smooth running sound. And usually, there will be a green indicator light on to show that the equipment is running normally. If the yellow fault light is on, stop the operation for scheduled inspection. Second, when using Chengfeng Zhizhi low temperature plasma cleaning equipment, special attention should be paid to the red warning light. Usually, the red light will be always on when there is a problem with the operation of the equipment or the jitter frequency is too fast. At this time, you should press the reset button immediately to observe If the equipment is still abnormal, the operation of the equipment should be stopped, and then the troubleshooting should be carried out to avoid damage to the equipment. Third, when using low-temperature plasma cleaning equipment, it should be cleaned regularly, and when cleaning, the power must be disconnected first, and then the vacuum chamber and electric control box must be opened, and attention should be paid to cleaning according to the specifications required in the manual. The vacuum chambers of many low-temperature plasma equipment are external toroidal electrodes, so it is not easy to cause contamination in the chamber. I hope the above explanation can help you, and you are welcome to inquire about this issue, and you can contact us if you need it.

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